Publications

2017

Angermueller, Christof; Lee, Heather J; Reik, Wolf; Stegle, Oliver

DeepCpG: accurate prediction of single-cell DNA methylation states using deep learning Journal Article

Genome Biology, 18 , pp. 67, 2017, ISSN: 1474-760X, (bibtex: angermueller_deepcpg:_2017).

Abstract | Links | BibTeX | Tags: Artificial neural network, Deep learning, DNA Methylation, epigenetics, machine learning, Single-cell genomics

Angermueller, Christof

Deep neural networks and statistical models for studying single-cell DNA methylation PhD Thesis

University of Cambridge, 2017.

Abstract | Links | BibTeX | Tags:

2016

Team, The Theano Development

Theano: A Python framework for fast computation of mathematical expressions Journal Article

arXiv:1605.02688 [cs], 2016, (arXiv: 1605.02688).

Abstract | Links | BibTeX | Tags: Computer Science - Learning, Computer Science - Mathematical Software, Computer Science - Symbolic Computation

Angermueller, Christof; Pärnamaa, Tanel; Parts, Leopold; Stegle, Oliver

Deep learning for computational biology Journal Article

Molecular Systems Biology, 12 (7), pp. 878, 2016.

Abstract | Links | BibTeX | Tags: cellular imaging, Computational Biology, Deep learning, machine learning, regulatory genomics

Angermueller, Christof; Clark, Stephen J; Lee, Heather J; Macaulay, Iain C; Teng, Mabel J; Hu, Tim Xiaoming; Krueger, Felix; Smallwood, Sébastien A; Ponting, Chris P; Voet, Thierry; Kelsey, Gavin; Stegle, Oliver; Reik, Wolf

Parallel single-cell sequencing links transcriptional and epigenetic heterogeneity Journal Article

Nature Methods, advance online publication , 2016, ISSN: 1548-7091.

Abstract | Links | BibTeX | Tags: epigenetics, Gene expression, Methylation analysis, RNA sequencing

2014

Smallwood, Sébastien A; Lee, Heather J; Angermueller, Christof; Krueger, Felix; Saadeh, Heba; Peat, Julian; Andrews, Simon R; Stegle, Oliver; Reik, Wolf; Kelsey, Gavin

Single-cell genome-wide bisulfite sequencing for assessing epigenetic heterogeneity Journal Article

Nature Methods, advance online publication , 2014, ISSN: 1548-7091.

Abstract | Links | BibTeX | Tags:

Winkler, Christiane; Krumsiek, Jan; Buettner, Florian; Angermueller, Christof; Giannopoulou, Eleni Z; Theis, Fabian J; Ziegler, Anette-Gabriele; Bonifacio, Ezio

Feature ranking of type 2 diabetes susceptibility genes improves prediction of type 1 diabetes Journal Article

Diabetologia, 2014, ISSN: 1432-0428.

Abstract | Links | BibTeX | Tags:

2013

Kaján, László; Yachdav, Guy; Vicedo, Esmeralda; Steinegger, Martin; Mirdita, Milot; Angermueller, Christof; Böhm, Ariane; Domke, Simon; Ertl, Julia; Mertes, Christian; Reisinger, Eva; Staniewski, Cedric; Rost, Burkhard

Cloud Prediction of Protein Structure and Function with PredictProtein for Debian Journal Article

BioMed Research International, 2013 , pp. 1–6, 2013.

Links | BibTeX | Tags:

Angermueller, Christof

Machine learning for predicting type 1 diabetes with high-throughput data Masters Thesis

Technical University Munich, 2013.

Abstract | Links | BibTeX | Tags:

2012

Angermueller, Christof; Biegert, Andreas; Söding, Johannes

Discriminative modelling of context-specific amino acid substitution probabilities. Journal Article

Bioinformatics (Oxford, England), 28 (24), pp. 3240–7, 2012.

Abstract | Links | BibTeX | Tags:

2011

Angermueller, Christof

Sequence searching using context-specific pseudocounts predicted by conditional random fields Masters Thesis

Technical University Munich, 2011.

Abstract | Links | BibTeX | Tags:

Lammens, Katja ; Bemeleit, Derk J; Möckel, Carolin ; Clausing, Emanuel ; Schele, Alexandra ; Hartung, Sophia ; Schiller, Christian B; Lucas, Maria ; Angermueller, Christof ; Söding, Johannes ; Strässer, Katja ; Hopfner, Karl-Peter

The Mre11:Rad50 structure shows an ATP-dependent molecular clamp in DNA double-strand break repair. Journal Article

Cell, 145 (1), pp. 54–66, 2011.

Abstract | Links | BibTeX | Tags:

See also Google Scholar.

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PhD Bioinformatics